Results 51 to 60 of about 88,012 (264)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Enhancing Forecast Verification in National Meteorological and Hydrological Services

Meteorological Applications
Forecast verification is an essential function of National Meteorological and Hydrological Services (NMHSs), underpinning their ability to deliver accurate, reliable, and actionable weather, climate, and water‐related information.
Thomas C. Pagano, Elizabeth E. Ebert, Mohammadreza Khanarmuei   +2 more
doaj   +1 more source

A Holistic Cybersecurity Maturity Assessment Framework for Higher Education Institutions in the United Kingdom

Applied Sciences, 2020
As organisations are vulnerable to cyberattacks, their protection becomes a significant issue. Capability Maturity Models can enable organisations to benchmark current maturity levels against best practices.
Aliyu Aliyu, Leandros Maglaras, Ying He, Iryna Yevseyeva, Eerke Boiten, Allan Cook, Helge Janicke   +6 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

SCALE SELF-ASSESSMENT OF PERSONAL MATURITY: ТНЕ EXPERIENCE IN THE DEVELOPMENT AND TESTING

Sovremennye Issledovaniâ Socialʹnyh Problem, 2017
Purpose. The article is devoted to substantive and psychometric characteristics to The Scale self-assessment of personal maturity. The scale developed on the socio-constructionist interpretation of the personal maturity’s criteria, which are considered ...
Anastasia Vladimirovna Miklyaeva
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Evaluating the Maturity and Obstacle Factors Affecting the Sichuan-Tibet Tourism Corridor, China

Redai dili
Tourism corridors are a new type of activity carrier with the advent of self-driving tours and transportation integration in tourism. Tourism corridors can help to reconstruct spatial tourism patterns and optimize regional tourism industry structures ...
Li Mi, Xi Jianchao, Ye Sui, Li Ziqiang, Huang Tai   +4 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Inclusive tool to assess lean manufacturing maturity and its relationship with the size or location of the company in Greater Montreal, Canada

Cogent Engineering
Manufacturing companies operate in aggressive environments and require high productivity for survival. This study examined the implementation status of lean manufacturing practices in a sample of Greater Montreal’s industries by assessing maturity levels
Didérot Déraillet Tadja, Fatma Lehyani, Samuel-Jean Bassetto, Alaeddine Zouari, Michel Tollenaere, Tony Wong   +5 more
doaj   +1 more source