Results 51 to 60 of about 5,910 (217)
Semantics of the maturity model for feature oriented domain analysis [PDF]
Computational Ecology and Software, 2015 Assessing the quality of a model has always been a challenge for researchers in academia and industry. The quality of a feature model is a prime factor in software development because it is used in the development of products.
M. Javed, M. Naeem, H. A. Wahab
doaj
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A Comprehensive Study of the IoT Cybersecurity in Smart Cities
IEEE Access, 2020 Smart cities exploit emerging technologies such as Big Data, the Internet of Things (IoT), Cloud Computing, and Artificial Intelligence (AI) to enhance public services management.
Roberto Omar Andrade +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Evaluating the Organizational Interoperability Maturity Level in ICT Research Center [PDF]
Journal of Information Technology Management, 2011 Interoperability refers to the ability to provide services and to accept services from other systems or devices. Collaborative enterprises face additional challenges to interoperate seamlessly within a networked organization.
Manijeh Haghighinasab, Samiyeh Khosravi
doaj
A Systematic Review of the Application of Maturity Models in Universities
Information, 2020 A maturity model is a widely used tool in software engineering and has mostly been extended to domains such as education, health, energy, finance, government, and general use.
Esteban Tocto-Cano +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Developing a Project Scorecard to Measure the Performance of Project Management in Relation to EFQM Excellence Model [PDF]
Amfiteatru Economic, 2017 Strategic company plans are more frequently realised in the form of strategic projects. Project portfolio management is new territory for a lot of companies, especially regarding the evaluation of strategic projects and the final financial and social ...
Mathias Scheiblich +3 more
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