Results 71 to 80 of about 148,818 (311)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

University maturity model – a bibliometric analysis

open access: yesEconomics and Environment
In today's dynamic and competitive environment, universities play a key role in generating, transmitting, and applying knowledge and innovation. The growing interest in evaluating university performance at national and international levels has led to ...
Joanna Szydło   +2 more
doaj   +1 more source

Evaluating the Organizational Interoperability Maturity Level in ICT Research Center [PDF]

open access: yesJournal of Information Technology Management, 2011
Interoperability refers to the ability to provide services and to accept services from other systems or devices. Collaborative enterprises face additional challenges to interoperate seamlessly within a networked organization.
Manijeh Haghighinasab, Samiyeh Khosravi
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Towards an integrated maturity model of asset management capabilities

open access: yes, 2014
Asset service organisations often recognize asset management as a core competence to deliver benefits to their business. But how do organizations know whether their asset management processes are adequate?
Dhakal, S.   +16 more
core   +1 more source

An Initial Maturity Model for Information Governance [PDF]

open access: yes, 2018
This report details the maturity model for information governance which will be used to assess the E-ARK Project use cases. The method that guides the application of this maturity model will then be detailed in deliverable 7.5, A Maturity Model consists
Anderson, David   +7 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Developing a Strategy to Align Multiple Governance Practices into a Single Global Supply Chain Management Policy? Methodology and Insights from the Primever Case Study

open access: yesProceedings of the Conference on Production Systems and Logistics
One of the most important issues in the logistics of perishable products is the problem of efficient handling of goods in the supply chain due to transportation problems and tracking requirements.
Filipas, Ioana   +6 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy