Results 91 to 100 of about 607,422 (297)

Which one? A suggested approach for evaluating digital health maturity models. [PDF]

Front Digit Health, 2022
Woods L, Eden R, Duncan R, Kodiyattu Z, Macklin S, Sullivan C.   +5 more
europepmc   +1 more source

Characterizing Distributions of Class III Milk Prices: Implications for Risk Management [PDF]

Descriptive statistics and time-series econometric models are used to characterize the behavior of monthly fluid milk prices. Prices in April, May and June appear to be more variable than those in subsequent months, and the spring-time prices are perhaps
Tomek, William G., Wang, Dabin
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A systematic literature review on quality maturity models [PDF]

Tehnika
This paper systematises the most commonly used maturity models of quality management systems in organisational systems. It is well known that the application of maturity models for quality management systems facilitates the improvement of organisational ...
Živković Nedeljka N., Glogovac Maja G., Milošević Isidora M.   +2 more
doaj   +1 more source

Dynamic Risk Profile of the US Term Structure by Wavelet MRA [PDF]

A careful examination of interest rate time series from different U.S. Treasury maturities by Wavelet Multiresolution Analysis (MRA) suggests that the first differences of the term structure of interest rate series are periodic or, at least, cyclic, non ...
CORNELIS A. LOS, SUTTHISIT JAMDEE
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

TINGKAT KEMATANGAN MANAJEMEN PROYEK: SURVEI DI BEBERAPA TEMPAT DI INDONESIA

Civil Engineering Dimension, 2005
This paper presents the results of a pilot survey aimed at ascertaining the level of project management maturity in Indonesian companies. Kerzner’s Level 2 assessment tool was used, which basically assesses maturity levels throughout the various phases
Achmad Fuad Bay, Connie Susilawati, Martin Skitmore   +2 more
doaj  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Advancing maturity modeling for precision oncology

Journal of Clinical and Translational Science
Introduction: This study aimed to map the maturity of precision oncology as an example of a Learning Health System by understanding the current state of practice, tools and informatics, and barriers and facilitators of maturity.
Ariella Hoffman-Peterson, Megh Marathe, Mark S. Ackerman, William Barnett, Reema Hamasha, April Kang, Kashmira Sawant, Allen Flynn, Jodyn E. Platt   +8 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source