Results 121 to 130 of about 121,608 (304)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
BUSSINES PROCESSES MATURITY MODELS
, 2014 V diplomski nalogi smo se osredotočili na modele zrelosti poslovnih procesov in podrobneje obravnavali osem modelov zrelosti (CMMI, BPMMM, BPMM-Fisher, PMMA, BPOMM, PEMM, BPMM-OMG in BPMM-Lee).
Sekulovska, Hristina
core +1 more source
Knowledge management maturity models - a morphological analysis
, 2010 A Knowledge Management Maturity Model is a structured approach for implementing Knowledge Management. Many practitioners and researchers have developed Knowledge Management Maturity Models, which have different forms, structure and characteristics ...
Baldev Raj, +3 more
core +1 more source
TINGKAT KEMATANGAN MANAJEMEN PROYEK: SURVEI DI BEBERAPA TEMPAT DI INDONESIA
Civil Engineering Dimension, 2005 This paper presents the results of a pilot survey aimed at ascertaining the level of project management maturity in Indonesian companies. Kerznerâs Level 2 assessment tool was used, which basically assesses maturity levels throughout the various phases
Achmad Fuad Bay +2 more
doaj
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Measuring innovation maturity – literature review on innovation maturity models
, 2019 In recent years it has noticed that innovation and innovativeness have become the basis for the success of not only individual business entities but entire regions and economies.
Inków, Monika
core
, 2021 Context: Applying maturity models to measure and evaluate Business Analytics (BA) in organisations is challenging. There is a lack of empirical studies on how BA maturity models are designed, assessed and validated to determine how BA contributes to ...
Lane, Michael +2 more
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source