Results 141 to 150 of about 121,608 (304)

Exploring knowledge management maturity from funcionalist and interpretivist perspectives

Entramado, 2015
The purpose of this article is to explore the Knowledge Management Maturity Model (KMMM) in big companies that are pioneers in the implementation of KM practices in Medellin, Colombia. The KMMM integrates the Funcionalist and Interpretivist perspectives
José Enrique Arias-Pérez, Carlos Mario Durango-Yepes   +1 more
doaj  

Research IT maturity models for academic health centers: Early development and initial evaluation. [PDF]

J Clin Transl Sci, 2018
Knosp BM, Barnett WK, Anderson NR, Embi PJ.   +3 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Capital structure: optimal leverage and maturity choice in a dynamic model [PDF]

, 2004
We introduce a dynamic model of optimal capital structure. Analytic solutions for the value of debt and equity are provided when the firm has the opportunity to issue new debt optimally at maturity of current debt.
Forte, Santiago
core  

Corrigendum: Research IT maturity models for academic health centers: Early development and initial evaluation. [PDF]

J Clin Transl Sci, 2019
Knosp BM, Barnett WK, Anderson NR, Embi PJ.   +3 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Term Structure of Volatility and Price Jumps in Agricultural Markets - Evidence from Option Data

Empirical evidence suggests that agricultural futures price movements have fat-tailed distributions and exhibit sudden and unexpected price jumps. There is also evidence that the volatility of futures prices contains a term structure depending on both ...
Koekebakker, Steen, Lien, Gudbrand D.
core   +1 more source

Maturity Models Development in IS Research: A Literature Review

, 2015
Maturity models are widespread in IS research and in particular, IT practitioner communities. However, theoretically sound, methodologically rigorous and empirically validated maturity models are quite rare.
Vatrapu, Ravi, Andersen, Kim Normann, Lasrado, Lester Allan   +2 more
core   +1 more source