Results 151 to 160 of about 121,608 (304)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

How agile are you? Discussing maturity levels of agile maturity models

open access: yes
With the emergence of agile software development methods, new approaches for determining agile maturity have become necessary. Other than for traditional maturity and capability models like CMMI and ISO/IEC 15504, the field of agile maturity models is ...
Vasylieva, Kseniia   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Which maturity is being measured? A classification of business process maturity models

open access: yes, 2010
. Today‟s organizations face the challenge to excel due to demanding customers. Hence, they are relying on their business processes to outperform competitors. Maturity models have been proposed to gradually assess and improve business processes. However,
Amy Van Looy   +5 more
core  

A measurement framework to assess software maturity models. [PDF]

open access: yesPeerJ Comput Sci
Alshareef R   +3 more
europepmc   +1 more source

The maturity of modeling [PDF]

open access: yesPhysics of Life Reviews, 2011
openaire   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

A REGRESSION ANALYSIS OF THE EFFECTS OF PLANTING DATE AND VARIETY ON CORN YIELDS IN MINNESOTA

open access: yes
This paper reports the results of a regression analysis of the relationship between planting date and corn yield. The study is based on experiments done at Agricultural Experiment Stations in Waseca, Lamberton and Morris, Minnesota.
Apland, Jeffrey   +2 more
core   +1 more source

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