Results 51 to 60 of about 121,608 (304)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Identification of key process areas in the production on an e-capability maturity model for UK construction organisations [PDF]
, 2010 Uptake of e-procurement by construction organisations has been slow (Martin, 2008). Positive e-business achievements in other industries, point towards the potential for the construction industry to accomplish similar results.
Eadie, Robert +3 more
core
Urban ScienceMunicipal smart city programs remain hampered by conceptual fragmentation and the absence of validated, context-specific maturity assessments. We develop the Smart Municipality Maturity Model (SMMM) via a design-science process, synthesizing 183 ...
Bernhard Koelmel +3 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Critical Review of Maturity Model Development in the Digitisation Era
Buildings, 2022 Maturity models assess the prevailing capability level and proffer the necessary capabilities for effective adoption in a systematic roadmap. This is considered essential to achieve diffusion of the emerging technologies.
Samuel Adeniyi Adekunle +4 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Comparison of maturity models [PDF]
, 2008 Maturity models are one of the widespread areas in the field of improving organizational performance. Maturity models identify organizational strengths and weaknesses in addition to providing benchmarking information. Project management maturity models
Osman, Omar, Khoshgoftar, Mohammad
core
A maturity model for Clinical Trials Management Ecosystem
Journal of Clinical and Translational ScienceIntroduction: Managing clinical trials is a complex process requiring careful integration of human, technology, compliance, and operations for success.
Shruti Sehgal +9 more
doaj +1 more source
Does Grade Level Matter for the Assessment of Business Process Management Maturity?
Naše Gospodarstvo, 2016 The purpose of this paper is to create and test the practical application of a business process management maturity assessment conducted at two different grade levels (management and professional level) in an organization.
Gabryelczyk Renata
doaj +1 more source