Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Feasibility Study of MOS Gas Sensors for Detecting Mineral Hydrocarbon Contaminants in Freshly Harvested Olives at Different Maturity Stages. [PDF]
Bonillo Martínez D +3 more
europepmc +1 more source
Assessment of Sensory and Texture Profiles of Grape Seeds at Real Maturity Stages Using Image Analysis. [PDF]
Cejudo-Bastante MJ +3 more
europepmc +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Growth Velocity and the Pubertal Growth Spurt Across Skeletal Maturity Stages in Class II Malocclusion: A Longitudinal Analysis. [PDF]
Kim NH +6 more
europepmc +1 more source
Effects of Additives on Silage Fermentation Characteristic and In Vitro Digestibility of Perennial Oat at Different Maturity Stages on the Qinghai Tibetan. [PDF]
Li P +8 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Effect of maturity stages on triglyceride and fatty acid profiles in olive oil from Zaity and Kaissy varieties grown in Syria. [PDF]
Jawad MA, Jawhar A, Dakah A, Ejbara MG.
europepmc +1 more source
Integrated metabolite analysis and health-relevant <i>in vitro</i> functionality of white, red, and orange maize (<i>Zea mays</i> L.) from the Peruvian Andean race <i>Cabanita</i> at different maturity stages. [PDF]
Ranilla LG +8 more
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

