Results 211 to 220 of about 542,377 (310)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Classification of Strawberry Maturity Stages and Varieties Using Neural Networks Based on Volatile Organic Compounds. [PDF]

Foods
Huang J, Zhang X, Yang H, Li Z, Xue Z, Wang Q, Zhang X, Ding S, Luo Z, Xu Y.   +9 more
europepmc   +1 more source

Pathogenicity of neutrophils linked to maturation stage in SLE [PDF]

Nature Reviews Rheumatology, 2019
openaire   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Effect of berry maturity stages on the germination and protein constituents of African nightshade (Solanum scabrum) seeds. [PDF]

Sci Rep
Ekhuya NA, Onyango MA, Senkler J, Winkelmann T, Bündig C.   +4 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Characterization of Maturation-Associated Genes in Ovary-Hepatopancreas Transcriptome and <i>Vitellogenin</i> Expression in Pacific Blue Swimming Crab <i>Callinectes arcuatus</i> During Gonadal Maturity Stages. [PDF]

Animals (Basel)
Montes-Dominguez AL, Avena-Soto JA, Borrego MI, Jimenez-Gutierrez LR.   +3 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Physical-Chemical Characterization of Fruit Harvested at Different Maturity Stages of Grafted Yellow Pitahaya (Selenicereus megalanthus Haw.). [PDF]

Plants (Basel)
Sanmiguel J, Andrade V, Vargas-Tierras Y, Samaniego I, Paredes-Arcos F, Vásquez-Castillo W, Viera-Arroyo W.   +6 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source