Status and future of recombinant adeno‐associated virus vector manufacturing
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Stress responsive miR-23a attenuates skeletal muscle atrophy by targeting MAFbx /atrogin-1 [PDF]
Muscle atrophy occurs in many pathological states and results primarily from accelerated protein degradation by the ubiquitin-proteasome pathway. We used dexamethasone to induce muscle wasting and investigated the role of a microRNA (miRNA) in the ...
Shigeru Miyaki +8 more
core
Lateral window maxillary sinus lift surgery: case report
The loss in height of the alveolar bone crest after tooth extraction makes rehabilitation of the posterior maxilla challenging due to low bone density and atrophy, in addition to pneumatization of the maxillary sinus.
Illa Oliveira Bitencourt FARIAS +4 more
doaj +1 more source
Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review
ABSTRACT Facial transplantation is a division of reconstructive surgery which aims to improve the function and appearance of a face that has endured severe disfigurement. Currently, the face transplant procedure uses allogenic tissue, harvested from a brain‐dead donor, to replace damaged facial components.
Olivia A. James, Faye Bennett
wiley +1 more source
Assessment and optimisation of MRI measures of atrophy as potential markers of disease progression in multiple sclerosis [PDF]
There is a need for sensitive measures of disease progression in multiple sclerosis (MS) to monitor treatment effects and understand disease evolution. MRI measures of brain atrophy have been proposed for this purpose. This thesis investigates a number
Anderson, V.
core
Dissociating memory networks in early Alzheimer's disease and frontotemporal lobar degeneration - a combined study of hypometabolism and atrophy [PDF]
Introduction: We aimed at dissociating the neural correlates of memory disorders in Alzheimer’s disease (AD) and frontotemporal lobar degeneration (FTLD).
Barbara Vogt +29 more
core +2 more sources
The Survey of Panoramic Radiographic Findings in Edentulous Patients in Isfahan City
Introductiion. There are a lot of edentulous patients who need complete dentures in any society. One of the most important problems of edentulous patients is remaining dental lesions.
M - Mehdizade, H Seyedmir
doaj
Dental rehabilitation is a major challenge for patients with severe jaw atrophy since the latter hinders the use of conventional dental implants. Virtual planning and CAD/CAM technologies have contributed to developing customized subperiosteal implants ...
Ángel Martínez-Sahuquillo Rico +5 more
doaj +1 more source
Abstract Background Guided bone regeneration is a reliable technique for treating alveolar ridge deficiencies, especially in cases of severe maxillary atrophy. This case report describes the clinical management of a partially edentulous female patient presenting horizontal bone resorption in the anterior maxilla.
Bruno Freitas Mello +3 more
wiley +1 more source
Avaliação do posicionamento maxilar no sentido ântero-posterior e vertical em pacientes submetidos à expansão rápida da maxila [PDF]
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.A expansão rápida da maxila é a separação da sutura palatina mediana, abrindo-a juntamente com a base esquelética da maxila, pelo uso de um aparelho ...
Pereira, Francyne Rakel
core

