Results 101 to 110 of about 282,015 (284)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Capacitated Facility Location Problem with Variable Coverage Radius in Distribution System
International Journal of Industrial Engineering and Production Research, 2010 The problem of locating distribution centers (DCs) is one of the most important issues in design of supply chain. In previous researches on this problem, each DC could supply products for all of the customers. But in many real word problems, DCs can only
M. S Jabalameli +2 more
doaj
Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers
FEBS Open Bio, EarlyView.Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo +4 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Gestão & Produção, 2009 O Problema Probabilístico de Localização-Alocação de Máxima Cobertura (PPLAMC) consiste em localizar facilidades, maximizando a população atendida e fornecendo um bom nível de serviço para toda a população, ou seja, deve-se garantir que um usuário, ao ...
Francisco de Assis Corrêa +2 more
doaj +1 more source
Quantitative Volume Space Form Rigidity Under Lower Ricci Curvature Bound
, 2017 Let $M$ be a compact $n$-manifold of $\operatorname{Ric}_M\ge (n-1)H$ ($H$ is a constant). We are concerned with the following space form rigidity: $M$ is isometric to a space form of constant curvature $H$ under either of the following conditions: (i)
Chen, Lina, Rong, Xiaochun, Xu, Shicheng
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Network Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
Finding maximal bicliques in bipartite networks using node similarity
Applied Network Science, 2019 In real world complex networks, communities are usually both overlapping and hierarchical. A very important class of complex networks is the bipartite networks. Maximal bicliques are the strongest possible structural communities within them.
Taher Alzahrani, Kathy Horadam
doaj +1 more source
Barrier subgradient method [PDF]
In this paper we develop a new primal-dual subgradient method for nonsmooth convex optimization problems. This scheme is based on a self-concordant barrier for the basic feasible set. It is suitable for finding approximate solutions with certain relative
NESTEROV, Y.
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