Results 81 to 90 of about 290,738 (260)

Estimation of airway obstruction using oximeter plethysmograph waveform data

open access: yesRespiratory Research, 2005
Background Validated measures to assess the severity of airway obstruction in patients with obstructive airway disease are limited. Changes in the pulse oximeter plethysmograph waveform represent fluctuations in arterial flow.
Desmond Renee' A   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Ultra‐Rapid Lispro results in accelerated insulin lispro absorption and faster early insulin action in comparison with Humalog® in Japanese patients with type 1 diabetes

open access: yesJournal of Diabetes Investigation, 2020
Aims/Introduction Ultra‐rapid lispro (URLi) is a novel ultra‐rapid mealtime insulin. This study compared the pharmacokinetic and glucodynamic profiles, safety, and tolerability of URLi and lispro (Humalog®) in Japanese patients with type 1 diabetes ...
Masanari Shiramoto   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Evaluation of Mechanical Parameters of Pellets

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016
The paper dealt with the evaluation of mechanical properties of the cylinder wheat straw, rapeseed straw and 50/50 % mixed wheat and rapeseed straw pellet samples. The pellets were made by the granulating machine MGL 200 (Kovonovak).
Ľubomír Kubík   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Force-dependent discharge of nematocysts in the sea anemone Haliplanella luciae (Verrill)

open access: yesBiology Open, 2012
Summary Sea anemones discharge cnidae (‘stinging capsules’ including nematocysts) to capture prey and to defend themselves. In the present study, we tested the relationship between the force of test probes striking feeding tentacles and discharge of ...
Dustin Todaro, Glen M. Watson
doaj   +1 more source

On maximizing curves of degree 7

open access: yesANNALI DELL'UNIVERSITA' DI FERRARA
AbstractIn the present paper we investigate an intriguing question on the existence of maximizing curves of degree 7 with some prescribed $$\textrm{ADE}$$ ADE singularities. We give a result proving the non-existence of such maximizing septics and we give new examples of conic-line arrangements with some $$\textrm{ADE}
openaire   +2 more sources

On maximal curves of $n$-correct sets

open access: yesCoRR
20 pages, 2 ...
Hakop Hakopian   +2 more
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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