Results 91 to 100 of about 232,120 (259)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Weighted Estimates for Rough Maximal Functions with Applications to Angular Integrability

open access: yesJournal of Function Spaces, 2019
In this note we establish certain weighted estimates for a class of maximal functions with rough kernels along “polynomial curves” on Rn. As applications, we obtain the bounds of the above operators on the mixed radial-angular spaces, on the vector ...
Feng Liu, Fangfang Xu
doaj   +1 more source

BAYESIAN IMAGE SEGMENTATION THROUGH LEVEL LINES SELECTION

open access: yesImage Analysis and Stereology, 2011
Bayesian statistical theory is a convenient way of taking a priori information into consideration when inference is made from images. In Bayesian image segmentation, the a priori distribution should capture the knowledge about objects. Taking inspiration
Charles Kervrann
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Examining the Force-Traces of Countermovement Jumps and Standing Broad Jumps for Kinematic Coordination Indicators

open access: yesBiomechanics
Background/Objectives: Jumping is a common movement pattern, often used in testing for both performance monitoring and decision-making in return to sport.
Hannah Schmidt   +2 more
doaj   +1 more source

A note on the Dancer–Fučík spectra of the fractional p-Laplacian and Laplacian operators

open access: yesAdvances in Nonlinear Analysis, 2015
We study the Dancer–Fučík spectrum of the fractional p-Laplacian operator. We construct an unbounded sequence of decreasing curves in the spectrum using a suitable minimax scheme. For p = 2, we present a very accurate local analysis.
Perera Kanishka   +2 more
doaj   +1 more source

The level of udder emptying and milk flow stability in Tsigai, Improved Valachian, and Lacaune ewes during machine milking

open access: yesCzech Journal of Animal Science, 2012
The objective of this investigation was to evaluate the stability of milk flow curves and the volume of residual milk in relation to milk flow curves in breeds Tsigai, Improved Valachian, and Lacaune (n = 16 heads per breed) milked twice daily. Milk flow
L. Mačuhová   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Families of curves and variation in moduli

open access: yesLe Matematiche, 2006
In this paper we study the class of smooth complex projective varieties B such that any modular morphism B → M_g  is constant for any g ≥ 2, giving structural properties and examples. Then we investigate the concept of the moduli dimension of a variety B;
Alessio Del Padrone, Ernesto Mistretta
doaj  

A note on certain maximal hyperelliptic curves

open access: yesFinite Fields and Their Applications, 2012
In this paper, the author gives necessary and sufficient conditions for a hyperelliptic curve of the form \(y^2=x^m+x\) to be maximal. More precisely, he proves that the curve \(y^2=x^{2g+1}+x\) is maximal over \(\mathbb{F}_{q^2}\) if and only if \(q\equiv -1\) or \(2g+1\pmod{4g}\), and the curve \(y^2=x^{2g+2}+x\) is maximal over the same field if and
openaire   +2 more sources

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