Results 101 to 110 of about 134,540 (296)
Maximal Sublattices And Frattini Sublattices Of Bounded Lattices [PDF]
, 1997 The Frattini sublattice (L) of a lattice L is the intersection of all maximal (proper) sublattices of L. In this note we are concerned with the following problems: (1) How many maximal sublattices can a finite lattice of size n have?
Schmid, Jürg +7 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Maximal Overgroups of Singer Elements in Classical Groups
Journal of Algebra, 2000 A Singer element in a finite classical group is an irreducible element of maximal order. They exist just for the linear groups, symplectic groups, orthogonal groups of minus type, and unitary groups in odd dimension. The paper under review gives an explicit list of all maximal subgroups containing Singer elements in the finite classical groups.
openaire +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Maximal entries of elements in certain matrix monoids
, 2017 Let $L_u=\begin{bmatrix}1 & 0\\u & 1\end{bmatrix}$ and $R_v=\begin{bmatrix}1 & v\\0 & 1\end{bmatrix}$ be matrices in $SL_2(\mathbb Z)$ with $u, v\geq 1$. Since the monoid generated by $L_u$ and $R_v$ is free, we can associate a depth to each element based on its product representation.
Han, Sandie +3 more
openaire +3 more sources
Orlicz-fractional maximal operators on weighted Lp spaces
Necessary and sufficient conditions for weight norm inequalities on Lebesgue spaces to hold are given in the scale of Orlicz spaces for the fractional Orlicz maximal operators which generalizes the fractional maximal operators. A similar argument for the
Sawano Y., Iida T.
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Numerical Study on the Explosive Separation of Pyrotechnic Cutter
Shock and Vibration, 2019 Pyrotechnic cutters are widely used in the wrapping-band connecting structures of carrier rockets. In this article, a three-dimensional (3D) finite element model of a pyrotechnic cutter is proposed to determine the influence of the explosive dynamic ...
Shihui Xiong +3 more
doaj +1 more source