Results 91 to 100 of about 177,831 (292)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
GENERATION OF SECOND MAXIMAL SUBGROUPS AND THE EXISTENCE OF SPECIAL PRIMES
Forum of Mathematics, Sigma, 2017 Let $G$ be a finite almost simple group. It is well known that $G$
TIMOTHY C. BURNESS +2 more
doaj +1 more source
Finding maximal torsion cosets on varieties
, 2007 We describe a new algorithm for finding all maximal torsion cosets on varieties over $\G_m^n$. We illustrate the algorithm with some examples.The starting point for this study is the search for points on a given variety whose coordinates are roots of ...
Aliev, Iskander, Smyth, Christopher
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Minimal and random generation of permutation and matrix groups
, 2012 We prove explicit bounds on the numbers of elements needed to generate various types of finite permutation groups and finite completely reducible matrix groups, and present examples to show that they are sharp in all cases.
Derek F. Holt +5 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
NUMERICAL ASPECTS OF THE SECONDARY MAGNETIC FIELD MAPPING IN MAGNETIC INDUCTION TOMOGRAPHY
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2017 Magnetic Induction Tomography (MIT) belongs to the noncontact electromagnetic imaging techniques. This paper focuses on determination of a secondary magnetic field map calculated with the help of the Biot-Savart law around the low-conductivity object ...
Beata Szuflitowska +2 more
doaj +1 more source
Condorcet choice functions and maximal elements
, 2003 Choice functions on tournaments always select the maximal element (Condorcet winner), provided they exist, but this property does not hold in the more general case of weak tournaments.
Subiza Martínez, Begoña +1 more
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On Lie algebras all of whose minimal subalgebras are lower modular. [PDF]
, 2004 The main purpose of this paper is to study Lie algebras L such that if a subalgebra U of L has a maximal subalgebra of dimension one then every maximal subalgebra of U has dimension one. Such an L is called lm(0)-algebra.
Kevin Bowman +5 more
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