Results 121 to 130 of about 177,831 (292)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Maximal elements in the Hurwitz graph
The Hurwitz graph has for vertices maximal chains in the lattice of non-crossing partitions, with an edge between two chains which differ at exactly one place. Adin and Roichman introduced an order on this graph by choosing a base element and showed that
Biane, Philippe
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Finite groups are big as semigroups
, 2011 We prove that a finite group G occurs as a maximal proper subsemigroup of an infinite semigroup (in the terminology of Freese, Ježek, and Nation, G is a big semigroup) if and only if |G| ≥ 3.
Ruskuc, Nik +3 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Comparison between different duals in multiobjective fractional programming
Open Mathematics, 2007 Boţ Radu, Chares Robert, Wanka Gert
doaj +1 more source
On maximal clones of ultrafunctions of rank 2
Известия Иркутского государственного университета: Серия "Математика", 2016 This paper considers functions mapping a 2-element set $A$ to all non-empty subsets of $A$. These functions are called ultrafunctions of rank 2. Ultrafunctions of rank 2 can be interpreted as functions on all non-empty subsets of $A$.
S. Zamaratskaya, V. Panteleev
doaj
Finding splitting elements and maximal tori in matrix algebras
, 1999 Roughly speaking, a splitting element of a matrix algebra is an element with a maximal number of eigenvalues. Using randomization, splitting elements can be found very easily and have proved to be extremely useful in computational representation theory ...
Ivanyos, G.
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source