Results 121 to 130 of about 12,649,601 (263)

Targeting pepsin provides superior protection to acid suppression in reflux‐associated airway inflammation and lung dysfunction

Experimental Physiology, EarlyView.
Abstract Gastro‐oesophageal reflux disease is a prevalent condition associated with extra‐oesophageal manifestations, such as pulmonary inflammation. Pepsin, an essential gastric enzyme, has been implicated in pulmonary complications owing to its inflammatory effects.
Thiago Meneses Araújo Leite Sales, Humberto Barbosa da Costa Filho, Kalinne Kelly Lima Gadelha, Kerolayne de Melo Nogueira, Álvaro Xavier Franco, Carlos Eduardo da Silva Monteiro, Maria Klayre Araújo de Sousa, Monalisa Cássias Souza, Isabele de Sá Silveira Melo, Lucas Antonio Duarte Nicolau, Marco Antonio de Freitas Clementino, Pedro Jorge Caldas Magalhães, Alexandre Havt, Pedro Marcos Gomes Soares, Daniel Sifrim, Marcellus Henrique Loiola Ponte de Souza   +15 more
wiley   +1 more source

Brain tissue pulsation responses to a low‐level expiratory resistance manoeuvre: A pilot healthy volunteer study

Experimental Physiology, EarlyView.
Abstract Pulsatility of the brain has been hypothesised to be linked to intracranial pressure (ICP), although the nature of this relationship remains poorly understood. We used a low‐level expiratory resistance manoeuvre to characterise brain tissue pulsation (BTP) responses in a pilot healthy volunteer study.
Jennifer K. Nicholls, Emma M. L. Chung, Jonathan Ince, Edward Pallett, Jatinder S. Minhas, Andrea Lecchini‐Visintini   +5 more
wiley   +1 more source

Eight-week of high-intensity running interval-training induce an improvement in maximal expiratory flow-volume curves in healthy prepubertal children

, 2003
International audienceSeveral studies have shown that respiratory muscle strength may be improved by aquatic physical activities in adults. This fact seem to be involved in the alterations of airway resistance or maximal expiratory flow-volume in ...
Berthoin, Serge, Deruelle, Fabien, Mucci, Patrick, Guinhouya, Benjamin, Nourry, Cédric, Fabre, Claudine, Baquet, Georges   +6 more
core   +1 more source

Stroke neurovascular responses to exercise: A novel rehabilitation paradigm

Experimental Physiology, EarlyView.
Abstract Stroke is a leading cause of long‐term disability, impacting the cerebrovascular, peripheral vascular and neuromotor systems. Characterising vascular responses to exercise post‐stroke offers valuable insights into the impairments that might influence outcomes during neurorehabilitation.
Alicen A. Whitaker‐Hilbig, Allison S. Hyngstrom, Matthew J. Durand   +2 more
wiley   +1 more source

Maximal expiratory flow-volume patterns in airway allergy.

We considered upper and lower airway allergies as different phases of airway allergy and MEFV patterns to vary according to the intensity of airway obstruction in maximal expiratory flow-volume and volume-time tests on fourteen patients with nasal ...
Meguro, Tadamichi, Yamanaka, Mayu, Nishioka, Keiko, Ogura, Yoshiro, Ogata, Masana   +4 more
core  

Thermoregulatory and plasma neurobiomarker responses to heat tolerance assessment in exertional heat illness and matched controls

Experimental Physiology, EarlyView.
Abstract Exercise in the heat and elevated tissue temperature are associated with neuronal stress and changes in blood–brain barrier (BBB) function. More severe thermal insult may manifest as exertional heat illness (EHI) and complication by central nervous system (CNS) dysfunction may persist post‐EHI.
Tom W. Palin, Jo Corbett, Lisa J. Hill, David R. Woods, Alex A. M. Gould, Barney Wainwright, James A. Roberts, Chloe N. Thomas, Daniel Snape, Carol House, Omar Tayari, Richard J. Elsworthy, James L. Mitchell, Andrew J. Roberts, John P. O'Hara, Michael J. Stacey   +15 more
wiley   +1 more source

Impact of living and training at low altitude for several years on endurance performance at higher altitude: Myth or reality

Experimental Physiology, EarlyView.
Abstract The physiological adaptations of long‐term high‐altitude residents without high‐altitude genetic ancestry remain poorly characterized. This study investigated whether permanent residence at low altitude (1200 m) influences performance at higher altitude (2500 m). We compared exercise responses at 2500 m in endurance‐trained athletes living for
Fabienne Durand, Sergi Brau Villaro, Antoine Raberin   +2 more
wiley   +1 more source

Age‐related loss of hysteresis in the spontaneous vascular sympathetic baroreflex is associated with altered neural rather than mechanical control

Experimental Physiology, EarlyView.
Abstract The vascular sympathetic baroreflex is critical for stabilising blood pressure. A notable feature of this reflex is hysteresis, a directional asymmetry in responsiveness during rising versus falling pressure that is evident in young adults but attenuated in older age.
Guto Wyn Hughes, Denis J. Wakeham, Christopher J. A. Pugh, Zoe H. Adams, Rachel N. Lord, Jonathan P. Moore   +5 more
wiley   +1 more source

Physical activity partly inhibits autonomic imbalance, immune dysfunction and quality of life induced by chronic shiftwork in policemen

Experimental Physiology, EarlyView.
Abstract Chronic shiftwork can impair autonomic cardiovascular regulation and immune homeostasis. However, the interaction between occupational status and physical activity level in military police officers remains incompletely understood. This cross‐sectional factorial study included 102 men stratified according to occupational status and physical ...
Hélida C. Aquino‐Santos, Jeanne S. Tavares‐Vasconcelos, Anamei Silva‐Reis, Maysa A. R. Brandão‐Rangel, Rayssa T. Morais‐Felix, Fernando A. Santa‐Rosa, André L. L. Bachi, Viviane Soares, Omid Salehian, Claudio R. Frison, Rodolfo P. Vieira, Regiane Albertini   +11 more
wiley   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source