Results 151 to 160 of about 11,564,321 (250)

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source

Challenges faced by adolescents and lung function technicians in Anuradhapura district, Sri Lanka, during spirometry: a qualitative study. [PDF]

Int Health
Perera D, Nayakarathne G, Chandrasiri P, Ananda K, Nuwangi H, Rajapakse S.   +5 more
europepmc   +1 more source

Mechanisms regulating cerebral perfusion during running exercise: Influence of foot strike‐induced pulsatility oscillations, CO2 reactivity and BP

The Journal of Physiology, EarlyView.
Abstract figure legend Young, healthy males and females completed an incremental running test, demonstrating a progressive increase in middle cerebral artery blood velocity (MCAv) up to maximal exercise despite reductions in end‐tidal CO2. To investigate the underlying mechanism, foot‐strike timing was synchronized to the diastolic phase of the cardiac
Lydia L. Simpson, Dean R. Perkins, Connor A. Howe, Christina D. Bruce, William K. Cornwell III, Justin S. Lawley   +5 more
wiley   +1 more source

Nonlinear association between P-wave axis and lung function in adult population with COPD: evidence from a cross-sectional study. [PDF]

Front Med (Lausanne)
Zhang N, Wang J, Zhao G, Yang R, Mao L, Xu J.   +5 more
europepmc   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

Validation and Clinical Analysis of the Quantitative COPD Exacerbation Recognition Tool (Q-CERT): Diagnostic Performance and Association with Lung Function Impairment. [PDF]

Int J Chron Obstruct Pulmon Dis
Zhao X, Zhou C, Liu Y, Cui K, Jones P, An Y, Zhang X.   +6 more
europepmc   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Association between IoT-driven dynamic pulmonary function monitoring and quality of life in community-dwelling patients with chronic obstructive pulmonary disease: a 2-year longitudinal study. [PDF]

Front Med (Lausanne)
Zhao M, Zheng H, Yang L, Yang M, Lin Y, Kong M, Wang N, Hang Y, Zhao Y.   +8 more
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Marked Clinical and Functional Response to Tezepelumab After Failure of Anti-Interleukin-5 (Anti-IL-5) Therapy in Severe Asthma. [PDF]

Cureus
Fujimoto M, Yanagihara T, Sakaki Y, Fujita M.   +3 more
europepmc   +1 more source