Results 161 to 170 of about 4,214 (224)

Cannabinoid CB1 allosteric ligands suppress inflammatory pain in male mice without tolerance, motor impairment, memory deficits or respiratory depression

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 20, Page 6132-6153, October 2026.
Abstract Background and Purpose Positive allosteric modulators (PAMs) engage sites distinct from the orthosteric CB1 cannabinoid receptor binding site. GAT211, a racemic ligand, contains GAT228 (R) and GAT229 (S) enantiomers. Whether enantiomer‐mediated differences in allosteric activation or positive allosteric modulation translate into differences in
Ifeoluwa D. Solomon   +3 more
wiley   +1 more source

How Does Progressivity Affect the Tax Cut Multiplier?

open access: yesInternational Economic Review, Volume 67, Issue 4, Page 1183-1209, October 2026.
ABSTRACT How does the targeting of personal income tax cuts affect the output multiplier? This paper provides quantitative evidence using a heterogeneous‐agent New‐Keynesian model calibrated to match US distributions of income, wealth, marginal tax rates, and marginal propensities to consume.
Christian Gillitzer
wiley   +1 more source

Cardiovascular Responses to Natural and Auditory Evoked Slow Waves Predict Post‐Sleep Cardiac Function

open access: yesJournal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT The importance of sleep as a key component of cardiovascular health has been increasingly recognized. Our previous research demonstrated that auditory‐enhanced slow waves increase cardiac function, but the underlying mechanisms behind these beneficial effects remain uncertain. In this study, we examined the influence of two types of slow waves
Giulia Alessandrelli   +16 more
wiley   +1 more source

Bicarbonate and Carbohydrate Co‐Ingestion During Exercise in a Novel Gel Format Improves Time‐Trial Performance After 3 h of Moderate‐Intensity Exercise in Trained Cyclists

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 10, October 2026.
ABSTRACT Sodium bicarbonate (SB) ingestion may improve high‐intensity exercise performance in efforts that range from 1 to 60 min; however, to date, no studies have investigated the effects of SB supplementation during exercise, nor its potential to attenuate the fatigue‐induced decline in parameters of the power‐duration curve during prolonged ...
Bernardo R. Norte   +11 more
wiley   +1 more source

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