Results 131 to 140 of about 69,010 (290)

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

open access: yesAdvanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini   +15 more
wiley   +1 more source

Factors Determining the Agreement between Aerobic Threshold and Point of Maximal Fat Oxidation: Follow-Up on a Systematic Review and Meta-Analysis on Association. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Ferri Marini C   +7 more
europepmc   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim   +6 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad   +3 more
wiley   +1 more source

Association between insulin resistance, lean mass and muscle torque/force in proximal versus distal body parts in healthy young men [PDF]

open access: yes, 2014
Objectives:The purpose of this study was to investigate whether there is already an association of insulin resistance (IR) with muscle mass and –force/torque in an adult population and whether this relationship is the same in distal and proximal body ...
Calders, Patrick   +7 more
core   +1 more source

Effect of habitual dietary carbohydrate on maximal fat oxidation in active but untrained humans

open access: yesAdvanced Exercise and Health Science
Changes in macronutrient intake has been linked to specific changes in rates of fat oxidation. However previous work has typically employed short duration interventions ranging from a couple of days to weeks.
Anneliese Blaxland   +3 more
doaj   +1 more source

Effects of 8-Week Anaerobic Gymnastics Training on Weight Loss and Related Growth Factors in Obese Children: A Clinical Trial

open access: yesJournal of Pediatrics Review, 2022
Background: Overweight and obesity are prominent threats to pediatric health. The prevalence of childhood obesity has dramatically been increasing worldwide.
Vahid Saleh, Roghayyeh Afroundeh
doaj  

Maximal fat oxidation rate in women with sedentary behaviour and at-risk body fat percentage [PDF]

open access: yesRevista chilena de nutrición, 2021
Gabriel E. Valdebenito   +4 more
openaire   +1 more source

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim   +11 more
wiley   +1 more source

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