Results 61 to 70 of about 693,697 (314)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

On a necessary condition for belonging of a function to periodic generalized Nikol’sky-Besov-Morrey space in terms of strong summability of Fourier series

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2016
This paper is dedicated to the investigation of strong summability in the generalized Morrey spaces. First, we study boundedness of the Hardy-Littlewood maximal function on generalized Morrey spaces.
Zh.Zh. Baituyakova
doaj  

On the integrability of the maximal ergodic function [PDF]

open access: yesProceedings of the American Mathematical Society, 1980
Let G = R
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Two open problems for absolutely convergent Dirichlet series [PDF]

open access: yesМатематичні Студії, 2012
For the absolutely convergent in a half-plane Dirichlet series we establish upper estimates without exceptional sets.
O. B. Skaskiv, O. Yu. Zadorozhna
doaj  

Maximizing Symmetric Submodular Functions [PDF]

open access: yesACM Transactions on Algorithms, 2015
Symmetric submodular functions are an important family of submodular functions capturing many interesting cases, including cut functions of graphs and hypergraphs. Maximization of such functions subject to various constraints receives little attention by current research, unlike similar minimization problems that have been widely studied. In this work,
openaire   +2 more sources

Maximal functions of plurisubharmonic functions [PDF]

open access: yesTsukuba Journal of Mathematics, 1992
Let \(B\) denote the unit ball in \(\mathbb{C}^ n\) \((n\geq 1)\) with boundary \(S\). For a function \(u:B\to\mathbb{C}\), the radial maximal function \({\mathcal M}u\) on \(S\) is defined by \[ {\mathcal M}u(\eta)=\sup\{| u(r\eta)|:0\leq r1\), \(\eta\in S\), let \(D_ \alpha(\eta)=\{z:| 1-\langle z,\eta\rangle|
Kim, Hong Oh, Park, Yeon Yong
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Fractional Maximal Functions in Metric Measure Spaces

open access: yesAnalysis and Geometry in Metric Spaces, 2013
We study the mapping properties of fractional maximal operators in Sobolev and Campanato spaces in metric measure spaces. We show that, under certain restrictions on the underlying metric measure space, fractional maximal operators improve the Sobolev ...
Heikkinen Toni   +3 more
doaj   +1 more source

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