Results 71 to 80 of about 693,697 (314)

ON MAXIMAL INITIAL DATA SET IN PROBLEMS OF PRACTICAL STABILITY OF DISCRETE SYSTEM

open access: yesМіжнародний науково-технічний журнал "Проблеми керування та інформатики", 2011
The properties of reachability sets of discrete system are substantiated on the basis of which the compactness of maximal set of initial conditions, the properties of its boundaries and interior points are proved.
A.N. Bashnyakov   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Variation of the Dyadic Maximal Function

open access: yesInternational Mathematics Research Notices, 2022
AbstractWe prove that for the dyadic maximal operator $\textrm {M}$ and every locally integrable function $f\in L^1_{{\textrm {loc}}}(\mathbb R^d)$ with bounded variation, also $\textrm {M} f$ is locally integrable and $\mathop {\textrm {var}}\textrm {M} f\leq C_d\mathop {\textrm {var}} f$ for any dimension $d\geq 1$.
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Functions of bounded variation, the derivative of the one dimensional maximal function, and applications to inequalities

open access: yes, 2007
We prove that if f: I ⊂ ℝ → ℝ is of bounded variation, then the uncentered maximal function M f is absolutely continuous, and its derivative satisfies the sharp inequality ∥DMf∥ L1(I) ≤ ∥Df∥(I).
Aldaz, null [0000-0001-8472-2606]   +1 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Parameter Estimation in Semi-Linear Models Using a Maximal Invariant Likelihood Function [PDF]

open access: yes
In this paper, we consider the problem of estimation of semi-linear regression models. Using invariance arguments, Bhowmik and King (2001) have derived the probability density functions of the maximal invariant statistic for the nonlinear component of ...
Jahar L. Bhowmik, Maxwell L. King
core  

The Boundedness of the Hardy-Littlewood Maximal Operator and Multilinear Maximal Operator in Weighted Morrey Type Spaces

open access: yesJournal of Function Spaces, 2014
The aim of this paper is to prove the boundedness of the Hardy-Littlewood maximal operator on weighted Morrey spaces and multilinear maximal operator on multiple weighted Morrey spaces. In particular, the result includes the Komori-Shirai theorem and the
Takeshi Iida
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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