Results 91 to 100 of about 660,454 (267)
Posets with maximal Möbius function
Journal of Combinatorial Theory, Series A, 1991 Let P be any finite poset. P is said to be bounded if it contains a unique minimal element \({\hat 0}\) and a unique maximal element \({\hat 1}\). The Möbius function of a bounded poset P is defined by \(\mu(P)=\mu (\hat 0,\hat 1)\). The question about the maximum absolute value of \(\mu(P)\) was posed by \textit{R. Stanley} [Enumerative Combinatorics,
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Maximization of Approximately Submodular Functions
CoRR12 ...
Thibaut Horel, Yaron Singer
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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A note on maximal operator on ℓ{pn} and Lp(x)(ℝ)
Journal of Function Spaces and Applications, 2007 We consider a discrete analogue of Hardy-Littlewood maximal operator on the generalized Lebesque space ℓ{pn} of sequences defined on ℤ. It is known a necessary and sufficient condition P which guarantees an existence of a real number p>1 such that the ...
Aleš Nekvinda
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
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The Pulmonary Function and Respiratory Muscle Strength in Thai Obese Children
Siriraj Medical Journal, 2007 Objective: This study was to compare the pulmonary function, respiratory muscle strength, and physical activity level between obese and non-obese children and to determine the correlation between pulmonary function, respiratory muscle strength and ...
Noppawan Charususin +3 more
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