Results 101 to 110 of about 693,697 (314)

Two results on the value distribution of meromorphic functions

open access: yesOpen Mathematics
In this article, we prove two results on the value distribution of meromorphic functions. Using the theorem of Yamanoi, the first result gives a precise estimation of the relationship between the characteristic function of a meromorphic function and its ...
Yang Degui, He Zhiying, Liu Dan
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Boundedness of the Hardy-Littlewood Maximal Function and the Strong Maximal Function on the Space BMO

open access: yes, 2018
In this thesis, we present the space BMO, the one-parameter Hardy-Littlewood maximal function, and the two-parameter strong maximal function. We use the John-Nirenberg inequality, the relation between Muckenhoupt weights and BMO, and the Coifman-Rochberg
Zhang, Wenhao
core  

On the radial maximal function of distributions [PDF]

open access: yesPacific Journal of Mathematics, 1986
We show that if the radial maximal function of a distribution \(f\in {\mathcal D}(R^ n)'\) belongs to \(L^ p(R^ n)\), then f belongs to \(H^ p(R^ n)\). This gives an affirmative answer to the question posed by Aleksandov and Havin.
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

On Maximal Function on the Laguerre Hypergroup [PDF]

open access: yes, 2006
2000 Mathematics Subject Classification: 42B20, 42B25, 42B35Let K = [0, ∞)×R be the Laguerre hypergroup which is the fundamental manifold of the radial function space for the Heisenberg group.
Assal, Miloud, Guliyev, Vagif
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Posets with maximal Möbius function

open access: yesJournal of Combinatorial Theory, Series A, 1991
Let P be any finite poset. P is said to be bounded if it contains a unique minimal element \({\hat 0}\) and a unique maximal element \({\hat 1}\). The Möbius function of a bounded poset P is defined by \(\mu(P)=\mu (\hat 0,\hat 1)\). The question about the maximum absolute value of \(\mu(P)\) was posed by \textit{R. Stanley} [Enumerative Combinatorics,
openaire   +2 more sources

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