Results 111 to 120 of about 693,697 (314)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Maximization of Approximately Submodular Functions
CoRR12 ...
Thibaut Horel, Yaron Singer
openaire +3 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Hardy–Littlewood maximal function of τ-measurable operators
, 2005 We define the Hardy–Littlewood maximal function of τ-measurable operators and obtain weak (1,1)-type and (p,p)-type inequalities for the Hardy–Littlewood maximal ...
Bekjan, Turdebek N., Turdebek N. Bekjan
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A note on maximal operator on ℓ{pn} and Lp(x)(ℝ)
Journal of Function Spaces and Applications, 2007 We consider a discrete analogue of Hardy-Littlewood maximal operator on the generalized Lebesque space ℓ{pn} of sequences defined on ℤ. It is known a necessary and sufficient condition P which guarantees an existence of a real number p>1 such that the ...
Aleš Nekvinda
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
BMO-Boundedness of Maximal Operators and g-Functions Associated with Laguerre Expansions
Journal of Function Spaces and Applications, 2012 Let {𝜑𝛼𝑛}𝑛∈ℕ be the Laguerre functions of Hermite type with index 𝛼. These are eigenfunctions of the Laguerre differential operator 𝐿𝛼=1/2(−𝑑2/𝑑𝑦2+𝑦2+1/𝑦2(𝛼2−1/4)). In this paper, we investigate the boundedness of the Hardy-Littlewood maximal function,
Li Cha, Heping Liu
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A selection of maximal elements under non-transitive indifferences
In this work we are concerned with maximality issues under intransitivity of the indifference. Our approach relies on the analysis of "undominated maximals" (cf., Peris and Subiza, J Math Psychology 2002).
Alcantud, José Carlos R. +2 more
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