Results 41 to 50 of about 1,329,079 (242)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
, 2022 Let R be a commutative ring with nonzero identity and S be a multiplicatively closed subset of R. An ideal P of R that is disjoint from S is called S-maximal ideal if there exists a fixed s ∈ S such that P ⊆ Q for some ideal Q of R implies either sQ ⊆ P or Q ∩ S ̸= ∅. In this study, first we give some relations between S-prime and S-maximal ideals that
Ersoy, Bayram Ali +2 more
openaire +4 more sources
Ideal Heat Engine Cycles at Maximal Efficiency—The Ideal Gas and Beyond
EntropyGiven a particular heat engine cycle, what is the optimal working medium that results in the highest efficiency? While one might jump to the conclusion that it must surely be the ideal gas, the situation is actually more intricate.
Gregory Behrendt, Sebastian Deffner
doaj +1 more source
The maximal ideals in quaternion orders [PDF]
Proceedings of the American Mathematical Society, 1971 Let R R be a Noetherian, integrally closed local domain, and Λ \Lambda an R R -order in a generalized quaternion algebra over the quotient field of R R . In this note, it is proved that: (a) Λ \Lambda has at most two maximal ideals; and (b) in case Λ ...
openaire +2 more sources
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Fuzzy small right ideals of rings [PDF]
Journal of Hyperstructures, 2013 We introduce the notion of fuzzy small right ideal,fuzzy small right prime ideal and fuzzy maximal small right ideal in a ring. We have obtained necessary and sufficient condition for a fuzzy small right ideal to be fuzzy small prime right ideal. We have
P. Dheena, G. Mohanraj
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Hybrid structure of maximal ideals in near rings
Complex & Intelligent SystemsA hybrid structure is an arrangement that makes use of many hierarchical reporting structures and is applied to algebraic structures such as groups and rings.
B. Jebapresitha
doaj +1 more source