Results 61 to 70 of about 1,329,079 (242)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Some results about ideals satisfying the condition Cn

open access: yesJournal of Taibah University for Science, 2017
We introduce, in this paper, a condition Cn that can be viewed as a generalization of the conditions C2 investigated recently by the present authors in [1,2,9,10].
Wahiba Messirdi, Charef Beddani
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Fuzzy Prime Ideal Theorem in Residuated Lattices

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2021
This paper mainly focuses on building the fuzzy prime ideal theorem of residuated lattices. Firstly, we introduce the notion of fuzzy ideal generated by a fuzzy subset of a residuated lattice and we give a characterization.
Pierre Carole Kengne   +2 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

3-standardness of the maximal ideal [PDF]

open access: yes, 2011
We study a notion called n-standardness (defined by M.E. Rossi (2000) in [10] and extended in this paper) of ideals primary to the maximal ideal in a Cohen–Macaulay local ring and some of its consequences.
Huneke, Craig   +3 more
core   +1 more source

On the reducible $M$-ideals in Banach spaces [PDF]

open access: yesSahand Communications in Mathematical Analysis, 2017
The object of the investigation is to study reducible $M$-ideals in Banach spaces. It is shown that if the number of $M$-ideals in a Banach space $X$ is $n(
Sajad Khorshidvandpour   +1 more
doaj  

The prime and maximal spectra and the reticulation of residuated lattices with applications to De Morgan residuated lattices

open access: yesOpen Mathematics, 2020
In this paper, by using the ideal theory in residuated lattices, we construct the prime and maximal spectra (Zariski topology), proving that the prime and maximal spectra are compact topological spaces, and in the case of De Morgan residuated lattices ...
Holdon Liviu-Constantin
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

A maximal theorem for holomorphic semigroups. [PDF]

open access: yes, 2004
Let X be a closed linear subspace of the Lebesgue space L^p(Omega ; mu); let -A be an invertible linear operator that is the generator of abounded holomorphic semigroup T_t on X.
Ian Doust   +3 more
core   +4 more sources

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