Results 151 to 160 of about 2,710,426 (336)

The maximal quartile operator

open access: yesRevista Matemática Iberoamericana, 2001
Let \(C^\Delta(\mathbb{R})\) denote the set of all functions \(f: \mathbb{R}\to\mathbb{R}\) that are finite linear combinations of characteristic functions of dyadic intervals, i.e., intervals of the form \([2^k n,2^k(n+ 1))\) with \(k,n\in\mathbb{Z}\).
openaire   +3 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Maximal inequality along curves associated with oscillatory integral operator

open access: yesJournal of Inequalities and Applications
In this paper, we establish maximal estimates along curves for a class of multiparameter oscillatory integral operators, which can be seen as an extension to the results of the Schrödinger type multiparameter operators of Sjolin and Soria (J. Math. Anal.
Yaoming Niu, Ying Xue
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Global Estimates for Singular Integrals of the Composition of the Maximal Operator and the Green's Operator

open access: yesJournal of Inequalities and Applications, 2010
We establish the Poincaré type inequalities for the composition of the maximal operator and the Green's operator in John domains.
Ling Yi, Umoh HansonM
doaj  

Commutators of maximal operator and sharp maximal operator on local Morrey-Lorentz spaces

open access: yesTRANSACTIONS ISSUE MATHEMATICS
Summary: In this paper, we study the boundedness of the maximal commutator operator \(M_b\), the commutators of the maximal operator \([b, M]\) and the commutators of the sharp maximal operator \([b, M^{\sharp}]\) in the local Morrey-Lorentz spaces \(M_{p,q; \lambda}^{\mathrm{loc}} (\mathbb{R}^n)\).
openaire   +3 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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