Results 131 to 140 of about 988,365 (280)
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
MAXIMAL HOMOTOPY LIE SUBGROUPS OF MAXIMAL RANK
, 1983 Let G be a compact connected Lie group with H a maximal connected compact subgroup of maximal rank. Then there is a fibration (phi):BH (---\u3e) BG with G/H as the fiber space.
FROHLIGER, JOHN ANTHONY
core +1 more source
, 2020 We argue that the spiral can, in presence of a maximum principle, be of maximal rank at a boundary, but does not preserve hypoellipticity.
openaire +2 more sources
Valuation domains with a maximal immediate extension of finite rank
, 2010 If R is a valuation domain of maximal ideal P with a maximal immediate extension of finite rank it is proven that there exists a finite sequence of prime ideals P=L0⊃L1⊃⋯⊃Lm⊇0 such that RLj/Lj+1 is almost maximal for each j, 0⩽j⩽m−1 and RLm is maximal if
Couchot, Francois
core
About the maximal rank of 3-tensors over the real and the complex number field
Tensor, Maximal rank,
Toshio Sumi +2 more
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Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Maximal subgroups of maximal rank in the classical algebraic groups [PDF]
Let $k$ be an arbitrary field. We classify the maximal reductive subgroups of maximal rank in any classical simple algebraic $k$-group in terms of combinatorial data associated to their indices.
Ganeshalingam, Vanthana +2 more
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Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source