Results 101 to 110 of about 5,399,796 (309)

Sequential Learning Of Profit Maximizing Sales Prices

, 2015
Sellers are interested in selling their products for the profit maximizing price. Often, this price is set based on an examination of the cost function of the product (Nagle, 2011), or it is based on market research querying customers price sensitivities
Parvinen, Petri, Petri Parvinen, Kaptein, Maurits; id_orcid, Maurits Kaptein   +3 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Maximizing vector distances using differential evolution - Relation to data redundancy [PDF]

, 2015
This paper studies how redundant data affect maximizing of weighted distances of vectors in a set of vectors. To maximize distances differential evolution is used, because the problem does not have analytical solution and is complex.
Jašek, Roman, Zuzana Kominkova Oplatkova, Martin Kolarik, Roman Jasek, Komínková Oplatková, Zuzana, Kolařík, Martin   +5 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay

Cell Reports
Summary: Developing an effective mRNA therapeutic often requires maximizing protein output per delivered mRNA molecule. We previously found that coding sequence (CDS) design can substantially affect protein output, with mRNA variants containing more ...
Alicia A. Bicknell, David W. Reid, Marissa C. Licata, Adriana K. Jones, Yi Min Cheng, Mengying Li, Chiaowen Joyce Hsiao, Christopher S. Pepin, Mihir Metkar, Yevgen Levdansky, Brian R. Fritz, Elizaveta A. Andrianova, Ruchi Jain, Eugene Valkov, Caroline Köhrer, Melissa J. Moore   +15 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Maximal sets without choice

Annals of Pure and Applied Logic
We show that it is consistent relative to ZF, that there is no well-ordering of $\mathbb{R}$ while a wide class of special sets of reals such as Hamel bases, transcendence bases, Vitali sets or Bernstein sets exists. To be more precise, we can assume that every projective hypergraph on $\mathbb{R}$ has a maximal independent set, among a few other ...
openaire   +3 more sources

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Construction of Optimal Trees for Maximizing Aggregation Information in Deadline- and Energy-Constrained Unreliable Wireless Sensor Networks

IEEE Access, 2018
In existing studies, the problem of maximizing aggregation information based on a given particular tree in deadlineand energy-constrained unreliable wireless sensor networks was addressed.
Yunquan Gao, Xiaoyong Li, Jirui Li, Yali Gao   +3 more
doaj   +1 more source

On maximal t-linearly independent sets

Journal of Combinatorial Theory, Series A, 1973
AbstractConsider a finite t + r − 1 dimensional projective space PG(t + r − 1, s) over a Galois field GF(s) of order s = ϱh, where ϱ and h are positive integers and ϱ is the prime characteristic of the field. A collection of k points in PG (t + r − 1, s) constitutes an L(t, k)-set if no t of them are linearly dependent.
Bodh Raj Gulati, Bruce Mck. Johnson, Uwe Koehn   +2 more
openaire   +2 more sources