Results 161 to 170 of about 5,399,796 (309)
Location-spatial interaction models: 1. Benefit-maximizing configurations of services
In three related papers the economic and spatial characteristics of a set of retail stores locating under welfare-maximizing and profit-maximizing criteria are explored.
K S Kim, H C W L Williams, D Martin
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Maximizing Throughput of Reliable Bulk Network Transmissions
, 1997 Maximizing Throughput of Reliable Bulk Network Transmissions by John W. Byers Doctor of Philosophy in Computer Science University of California at Berkeley Professor Christos Papadimitriou, Chair We study combinatorial optimization and on-line scheduling
John W. Byers
core
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
The economics of payment card fee structure: what drives payment card rewards? [PDF]
This paper investigates potential market forces that cause payment card rewards even when providing payment card rewards is not the most efficient. Three factors-oligopolistic merchants, output-maximizing card networks, and the merchant's inability to ...
Fumiko Hayashi
core
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Welfare-Maximizing Correlated Equilibria with an Application to Wireless Communication
The set of correlated equilibria is convex and contains all Nash equilibria as special cases. Thus, the social welfare-maximizing correlated equilibrium is amenable to convex analysis and offers social welfare that is at least as good as the game s best ...
Rustem, Berç, Kong, Fook, Kuhn, Daniel
core +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source