Results 141 to 150 of about 5,399,796 (309)
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Maximal Independent Sets and Separating Covers
The American Mathematical Monthly, 2011 In 1973, Katona raised the problem of determining the maximum number of subsets in a separating cover on n elements. The answer to Katona's question turns out to be the inverse to the answer to a much simpler question: what is the largest integer which is the product of positive integers with sum n?
openaire +3 more sources
, 2019 The supplementary material for paper "Rui Li, Wolfgang Heidrich, Hierarchical and View-invariant Light Field Segmentation by Maximizing Entropy Rate on 4D Ray Graphs.
Li, Rui, Heidrich, Wolfgang
core +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Every ergodic measure is uniquely maximizing
, 2008 . Let Mφ denote the set of Borel probability measures invariant under a topological action φ on a compact metrizable space X. For a continuous function f: X → R, a measure µ ∈ Mφ is called f-maximizing if f dµ = sup { f dm: m ∈ Mφ}. It is shown that
Oliver Jenkinson
core
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Non-unitarity maximizing unraveling of open quantum dynamics
SciPost PhysicsThe dynamics of many-body quantum states in open systems is commonly numerically simulated by unraveling the density matrix into pure-state trajectories.
Ruben Daraban, Fabrizio Salas-Ramírez, Johannes Schachenmayer
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Maximizing the Benefits of Transitway Investment
, 2012 In the Twin Cities metropolitan area, significant long-range transit planning activities have been ongoing since the late 1990s. By 2030, the region is expected to have a network of fourteen transitways converging on the Minneapolis and St. Paul downtown
Fan, Yingling, Tilahun, Nebiyou Y.
core