Results 131 to 140 of about 5,399,796 (309)

Maximizing the probability of attaining a target prior to extinction

open access: yes, 2011
International audienceWe present a dynamic programming-based solution to the problem of maximizing the probability of attaining a target set before hitting a cemetery set for a discrete-time Markov control process. Under mild hypotheses we establish that
Eugenio Cinquemani   +5 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Maximizing Sets and Fuzzy Markoff Algorithms

open access: yes, 2008
—A fuzzy algorithm is an ordered set of fuzzy instructions that upon execution yield an approximate solution to a given problem. Two unrelated aspects of fuzzy algorithms are considered in this paper.

core  

Value of dynamic revenue-maximizing congestion pricing in a highly congested corridor

open access: yes, 2017
This paper examines the value of utilizing dynamic, revenue-maximizing, congestion pricing on a privately operated tolled route, when the only alternative is a highly congested, public, free-access route.
El Khoury, John, Srour, F. Jordan
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Fuzzy Soft Sets and its Application to Decision Making: A Short Case Study Involving the Health Sector [PDF]

open access: yes
The health sector faces uncertainty and complex decision-making scenarios, making traditional analytical tools insufficient. The fuzzy soft set theory has emerged as a powerful framework for modeling and reasoning with uncertain information, with ...
Adebisi, Sunday Adesina   +1 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Normal wiggly probabilistic hesitant fuzzy-based TODIM approach for optimal solid waste disposal method selection

open access: yesHeliyon
The normal wiggly probabilistic hesitant fuzzy set (NWPHFS) enhances the conventional probabilistic hesitant fuzzy set (PHFS) by capturing not only explicit probabilistic information but also critical underlying details that may be hidden in the original
Jawad Ali, Dragan Pamucar
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy