Results 141 to 150 of about 105,583 (339)

Assessment of cadmium and lead concentration in rainbow trout (Oncorhynchus mykiss) and calculation the food consumption risk

open access: yesسلامت و محیط, 2018
Background and Objective: Heavy metals as a main group of aquatic pollutants cause poisoning and concern in fish consumption. The aim of the present study was to assess cadmium (Cd) and lead (Pb) concentration in liver and muscle of rainbow trout ...
H Tahsini, M Ahmadpour, MH Sinkakarimi
doaj  

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

Tubing specifications selection and its effect on the results of hydraulic fracturing treatment in oil formations [PDF]

open access: yes
Equipment specification, data collection and design process are critical factors for any hydraulic fracturing treatment success. This paper investigates tubing specifications selection and its effect on the results of hydraulic fracturing treatment ...
Abuhatira, A.   +2 more
core  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

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