Results 81 to 90 of about 4,606,141 (253)

STATISTICAL EVALUATION OF DATA ON THE POLLUTION OF THE PRUT RIVER WITH AMMONIUM NITROGEN

Journal of Engineering Science (Chişinău)
This paper analyzes the pollution of the Prut River with ammonium nitrogen (NH₄⁺) during the period 2019–2021, focusing on exceedances of the maximum allowable concentration (MAC) of 0.2 mg/L.
MARUSIC, Galina, BRANIȘTE, Rodica, SAVA, Nina, ABABII, Victor, CĂRBUNE, Viorel, TIHOLAZ, Tamara   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Connecticut and federal maximum allowable truck weights

, 2002
Electronic data.; Title from title screen.; "April 25, 2002."; Compares Connecticut's maximum allowable truck weights and those under federal law.; Harvested from the web on 3/6 ...
Fazzalaro, James J.
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

DETERMINATION OF MAXIMUM ALLOWABLE CONCENTRATION AND LC5096H OF SEFIDROUD RIVER SEDIMENTS FOR PERSIAN STURGEON (ACIPENSER PERSICUS) FINGERLINGS

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2007
The impact of Sefidroud River sediments on the fingerlings of Persian Sturgeon (Acipenser persicus) was studied in 2005. The tests were done in 20 liter aquariums each containing 10 Persian Sturgeons fingerlings weighing 3-5 grams each.
M. Yosefi garakoei; Sh. Nezami; K. Mehdi nezhad; H. Khara; Z. Pazhand; M. Mohmmad nezhad
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Water quality aspects from Spanish sites to support managed aquifer recharge (MAR) guidelines not based on maximum allowable concentration standards

Acque Sotterranee
Most countries that have technical guidelines or regulations for artificial recharge or managed aquifer recharge (MAR), that include water quality aspects are based on the establishment of standards or Maximum Allowable Concentrations (MACs) to regulate
Enrique Fernandez-Escalante, José David Henao Casas, Rodrigo Calero Gil   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

ENVIRONMENTAL SIGNIFICANCE OF URANIUM CONTENTS IN DRINKING WATEROF THE SIWA OASIS, WESTERN DESERT, EGYPT

Journal of Environmental Science, 2018
Within this work, the 238U activity concentration has been measured indrinking water samples collected from drinking waterresources in siwa oasis. Measurement of 238U activity concentrations in the examined samples was carried out by gamma-spectrometer ...
Abd El Hay, Lamis, S., Gad, A., El Malky, M. G.   +2 more
doaj   +1 more source