Results 81 to 90 of about 4,366,934 (248)
Determination of the maximum allowable gas pressure for an underground gas storage salt cavern – A case study of Jintan, China [PDF]
, 2019 Increasing the allowable gas pressure of underground gas storage (UGS) is one of the most effective methods to increase its working gas capacity. In this context, hydraulic fracturing tests are implemented on the target formation for the UGS construction
Tongtao Wang +11 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Design of a GaInP/GaAs tandem solar cell for maximum daily, monthly, and yearly energy output [PDF]
, 2011 Solar concentrator cells are typically designed for maximum efficiency under the AM1.5d standard spectrum. While this methodology does allow for a direct comparison of cells produced by various laboratories, it does not guarantee maximum daily, monthly ...
Haas, Alexander W. +3 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2007 The impact of Sefidroud River sediments on the fingerlings of Persian Sturgeon (Acipenser persicus) was studied in 2005. The tests were done in 20 liter aquariums each containing 10 Persian Sturgeons fingerlings weighing 3-5 grams each.
M. Yosefi garakoei; Sh. Nezami; K. Mehdi nezhad; H. Khara; Z. Pazhand; M. Mohmmad nezhad
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Acque SotterraneeMost countries that have technical guidelines or regulations for artificial recharge or managed aquifer recharge (MAR), that include water quality aspects are based on the establishment of standards or Maximum Allowable Concentrations (MACs) to regulate
Enrique Fernandez-Escalante +2 more
doaj +1 more source
Use of a Simple Age-Structured Bioeconomic Model to Estimate Optimal Long-Run Surpluses [PDF]
When the New Zealand government introduced individual transferable quotas for major commercial fish stocks, the initial allocation for some stocks exceeded their total allowable catches and made it necessary to buy back immediately some of the quota ...
Gilbert, David John
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source