Results 51 to 60 of about 563,674 (272)

ESTIMATING VOLUME DISTRIBUTIONS USING MAXIMUM ENTROPY

Image Analysis and Stereology, 2011
This paper describes a new method for estimating particle volume distributions using isotropic, uniform, random (IUR) sections. An attractive feature of the method is that it makes no assumptions about the shape of the particles.
Jonathan M Keith, Stephen L Gay
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Continuity of the Maximum-Entropy Inference

, 2014
We study the inverse problem of inferring the state of a finite-level quantum system from expected values of a fixed set of observables, by maximizing a continuous ranking function.
A. Caticha, A. Uhlmann, A. Wehrl, B. Groisman, B. Li, C. Berge, D. Greenberger, D. Henrion, D. Leung, D. Petz, E. Schrödinger, E.B. Davies, E.H. Wichmann, E.M. Alfsen, E.T. Jaynes, F. Topsøe, H. Hasegawa, H. Umegaki, I. Bjelaković, I. Csiszár, I. Csiszár, I. Csiszár, I. Csiszár, I. Voigt, J. Chen, J. Uffink, K. Modi, L. Boltzmann, M.A. Nielsen, M.B. Ruskai, M.E. Shirokov, N. Ay, O. Barndorff-Nielsen, O. Bratteli, R.M. Dudley, R.S. Ingarden, R.T. Rockafellar, S. Papadopoulou, S. Weis, S. Weis, S.A. Ali, S.H. Ayupov, S.N. Karbelkar, T. Netzer, V. Bužek, V.Y. Protasov, Weis Stephan, Å. Lima   +47 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Estimation Bias in Maximum Entropy Models

Entropy, 2013
Maximum entropy models have become popular statistical models in neuroscience and other areas in biology and can be useful tools for obtaining estimates of mutual information in biological systems.
Jakob H. Macke, Iain Murray, Peter E. Latham   +2 more
doaj   +1 more source

Moments of the maximum entropy and the symmetric maximum entropy distribution

Economics Letters, 1981
Abstract Simulation results are described for four estimators of moments of a normal distribution: the sample and maximum entropy (ME) moments and those obtained when the sample or ME distribution is symmetrized. The discussion includes the small-sample bias and the gain in efficiency which results from the knowledge that the parent distribution is ...
University of Chicago, Chicago, IL 60637, USA ( host institution ), Theil, Henri ( author ), Kidwai, Sartaj A. ( author )   +2 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A link between the maximum entropy approach and the variational entropy form

, 2010
The maximum entropy approach operating with quite general entropy measure and constraint is considered. It is demonstrated that for a conditional or parametrized probability distribution $f(x|\mu)$ there is a "universal" relation among the entropy rate ...
E. V. VAKARIN, J. P. BADIALI, Jaynes E. T.   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source