Results 61 to 70 of about 2,408,709 (295)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The minimum local cross-entropy criterion for inferring risk-neutral price distributions from traded options prices [PDF]
, 2004 A quantity known as the Local Cross-Entropy (LCE) for a density is proposed, defined to be the local derivative of the Cross-Entropy between a density and a ’kernel-smoothed’ version of itself, with respect to bandwidth of the smoothing.
Edelman, David
core +1 more source
Maximum Entropy Production vs. Kolmogorov-Sinai Entropy in a Constrained ASEP Model
Entropy, 2014 The asymmetric simple exclusion process (ASEP) has become a paradigmatic toy-model of a non-equilibrium system, and much effort has been made in the past decades to compute exactly its statistics for given dynamical rules.
Martin Mihelich +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Information Entropy Production of Maximum Entropy Markov Chains from Spike Trains
Entropy, 2018 The spiking activity of neuronal networks follows laws that are not time-reversal symmetric; the notion of pre-synaptic and post-synaptic neurons, stimulus correlations and noise correlations have a clear time order.
Rodrigo Cofré, Cesar Maldonado
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Maximum Entropy, Parallel Computations and Lotteries
, 1998 By picking unpopular sets of numbers in a lottery, it is possible to increase one’s expected winnings. We have used the Maximum Entropy method to estimate the probability of each of the 14 million tickets being chosen by players in the UK National ...
Daniell, G.J., Nicole, D.A., Cox, S.J.
core +1 more source
Entropy, 2013 It has been suggested that the maximum entropy production (MEP) principle, or MEP hypothesis, could be an interesting tool to compute climatic variables like temperature.
Corentin Herbert, Didier Paillard
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source