Results 101 to 110 of about 3,138,878 (297)
A Maximum Entropy Procedure to Solve Likelihood Equations
Entropy, 2019 In this article, we provide initial findings regarding the problem of solving likelihood equations by means of a maximum entropy (ME) approach. Unlike standard procedures that require equating the score function of the maximum likelihood problem at zero,
Antonio Calcagnì +3 more
doaj +1 more source
SIMULATED MAXIMUM LIKELIHOOD FOR DOUBLE-BOUNDED REFERENDUM MODELS [PDF]
Although joint estimation of referendum-type contingent value (CV) survey responses using maximum-likelihood models is preferred to single-equation estimation, it has been largely disregarded because estimation involves evaluating multivariate normal ...
Riddel, Mary C.
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Reducing the bias of the maximum likelihood estimator for the Poisson regression model [PDF]
We derive expressions for the first-order bias of the MLE for a Poisson regression model and show how these can be used to adjust the estimator and reduce bias without increasing MSE.
Hui Feng, David E Giles
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Approximate regularised maximum-likelihood approach for censoring outliers
The Journal of Engineering, 2019 This study considers censoring outliers in a radar scenario with limited sample support. The problem is formulated as obtaining the regularised maximum likelihood (RML) estimate of the outlier index set.
Sudan Han +5 more
doaj +1 more source
The breakdown behavior of the maximum likelihood estimator in the logistic regression model. [PDF]
: In this note we discuss the breakdown behavior of the Maximum Likelihood (ML) estimator in the logistic regression model. We formally prove that the ML-estimator never explodes to infinity, but rather breaks down to zero when adding severe outliers to ...
Croux, Christophe +2 more
core
Noncoherent Maximum Likelihood Detection for Differential Spatial Multiplexing MIMO Systems [PDF]
, 2010 In this paper, we propose a novel noncoherent maximum likelihood detection (NMLD) method for differential spatial multiplexing (SM) multiple-input multiple-output (MIMO) systems.
Handa, Shiro +4 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source