Results 71 to 80 of about 288,039 (268)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A novel efficient estimator for three‐dimensional bearings‐only source localisation with unknown sensor altitude and systematic measurement errors

IET Radar, Sonar & Navigation
A novel two‐stage profile maximum likelihood estimator is proposed to estimate the source location and the systematic errors jointly, with the aim of addressing the problem of source localisation using angle‐only measurements from a single sensor with ...
Heng‐Yu Hu, Ji‐An Luo, Dong‐Liang Peng   +2 more
doaj   +1 more source

Method of estimation of frequency parameters of ultra-wideband signals with an unknown spectrum shape in the presence of interference

Физика волновых процессов и радиотехнические системы
Background. One of the urgent tasks of processing ultra-wideband signals is the assessment of their frequency parameters in complex signal-noise conditions. Aim.
The Tuan Doan, Pavel A. Trifonov
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The Generalized Exponential Distribution As a Lifetime Model under Different Loss Functions

Data Science Journal, 2009
Bayes estimates of the unknown parameter and the reliability function for the generalized exponential model are derived. Bayes estimates are obtained under various losses such as the squared error, the absolute error, the squared log error, and the ...
A Asgharzadeh, R Rezaei
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Frequency Diversity Array for DOA Estimation [PDF]

Mehran University Research Journal of Engineering and Technology, 2017
The localization of targets has been presented in this article. DOA (Direction of Arrival) is an important parameter to be determined by radar. The MLE (Maximum Likelihood Estimator) has been widely used to accurately and efficiently estimate the DOAs ...
NAUMAN ANWAR BAIG, MOHAMMAD BILAL MALIK, MUHAMMAD ZEESHAN   +2 more
doaj  

A Bivariate Discrete Lindley Distribution and Applications [PDF]

المجلة العلمية للدراسات والبحوث المالية والتجارية
In this paper a bivariate discrete Lindley distribution has been derived from a discrete Lindely distribution using Farlie-Gumbel-Morgenstern copula. Some properties of this distribution such as probability generating function, conditional distributions,
Yasser Amer, Dina Abdelhady, Rania Shalabi   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Properties and Inference for a New Class of Generalized Rayleigh Distributions with an Application

Open Mathematics, 2019
In the present paper, we introduce a new form of generalized Rayleigh distribution called the Alpha Power generalized Rayleigh (APGR) distribution by following the idea of extension of the distribution families with the Alpha Power transformation.
Biçer Hayrinisa Demirci
doaj   +1 more source