Results 121 to 130 of about 208,181 (263)
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
"Within-Trial" Prognostic Score Adjustment Is Targeted Maximum Likelihood Estimation. [PDF]
Højbjerre-Frandsen E, Schuler A.
europepmc +1 more source
Smoothed simulated pseudo-maximum likelihood estimation for nonlinear mixed effects models with censored responses. [PDF]
Song Y, Wang R.
europepmc +1 more source
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
Regularized Joint Maximum Likelihood Estimation of Latent Space Item Response Models. [PDF]
Molenaar D, Jeon M.
europepmc +1 more source
Targeted maximum likelihood estimation of causal effects with interference: A simulation study. [PDF]
Zivich PN +5 more
europepmc +1 more source
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source
Prenatal paracetamol exposure and wheezing in infancy: a targeted maximum likelihood estimation application. [PDF]
Moccia C +11 more
europepmc +1 more source
Reducing computational demands of restricted maximum likelihood estimation with genomic relationship matrices. [PDF]
Meyer K.
europepmc +1 more source
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source

