Encoding force modulation in two electrotactile feedback parameters strengthens sensory integration according to maximum likelihood estimation. [PDF]
Gholinezhad S +3 more
europepmc +1 more source
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Maximum likelihood estimation of log-affine models using detailed-balanced reaction networks. [PDF]
Henriksson O +3 more
europepmc +1 more source
Simultaneous Maximum Likelihood Estimation for Piecewise Linear Instrumental Variable Models. [PDF]
Liu SS, Zhu Y.
europepmc +1 more source
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
Maximum likelihood estimation under the Emax model: existence, geometry and efficiency. [PDF]
Aletti G, Flournoy N, May C, Tommasi C.
europepmc +1 more source
Association of globalization with the burden of opioid use disorders 2019. A country-level analysis using targeted maximum likelihood estimation. [PDF]
Barbalat G, Reddy G, Franck N.
europepmc +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Transfering Targeted Maximum Likelihood Estimation for Causal Inference into Sports Science. [PDF]
Dijkhuis TB, Blaauw FJ.
europepmc +1 more source
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source

