Results 51 to 60 of about 1,223,755 (370)

Targeted maximum likelihood estimation for a binary treatment: A tutorial

Statistics in Medicine, 2018
When estimating the average effect of a binary treatment (or exposure) on an outcome, methods that incorporate propensity scores, the G‐formula, or targeted maximum likelihood estimation (TMLE) are preferred over naïve regression approaches, which are ...
M. Luque-Fernández, M. Schomaker, B. Rachet, M. Schnitzer   +3 more
semanticscholar   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Maximum likelihood estimation for Gaussian process with nonlinear drift

Nonlinear Analysis, 2018
We investigate the regression model Xt = θG(t) + Bt, where θ is an unknown parameter, G is a known nonrandom function, and B is a centered Gaussian process.
Yuliya Mishura, Kostiantyn Ralchenko, Sergiy Shklyar   +2 more
doaj   +1 more source

Maximum likelihood estimation in log-linear models

, 2012
We study maximum likelihood estimation in log-linear models under conditional Poisson sampling schemes. We derive necessary and sufficient conditions for existence of the maximum likelihood estimator (MLE) of the model parameters and investigate ...
Fienberg, Stephen E., Rinaldo, Alessandro   +1 more
core   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

MaxEnt assisted MaxLik tomography

, 2004
Maximum likelihood estimation is a valuable tool often applied to inverse problems in quantum theory. Estimation from small data sets can, however, have non unique solutions.
Hradil, Z., Rehacek, J.
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Maximum Likelihood Estimation Based Nonnegative Matrix Factorization for Hyperspectral Unmixing

Remote Sensing, 2021
Hyperspectral unmixing (HU) is a research hotspot of hyperspectral remote sensing technology. As a classical HU method, the nonnegative matrix factorization (NMF) unmixing method can decompose an observed hyperspectral data matrix into the product of two
Qin Jiang, Yifei Dong, Jiangtao Peng, Mei Yan, Yi Sun   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Usage of Penalized Maximum Likelihood Estimation Method in Medical Research: An Alternative to Maximum Likelihood Estimation Method

Journal of Research in Medical Sciences, 2008
<p style="text-align: justify"><span>The present paper was to reduce biased estimation using new approach (Penalized Maximum Likelihood Estimation Method) in Logistic Regression. It was assumed in the present paper that four various data sets
Ecevit Eyduran
doaj