Results 61 to 70 of about 1,223,755 (370)
Implementing and evaluating the nested maximum likelihood estimation technique [PDF]
Tutorials in Quantitative Methods for Psychology, 2007 Estimating parameters describing response time distributions is difficult. The most commonly used method for parameter estimation is the maximum likelihood method (ML).
Denis Cousineau
doaj
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
On the Interpolating Family of Distributions
AxiomsA recent paper introduced the interpolating family (IF) of distributions, and they also derived various mathematical properties of the family. Some of the most important properties discussed were the integer order moments of the IF distributions.
Saralees Nadarajah, Idika E. Okorie
doaj +1 more source
Characterising a universal cloning machine by maximum-likelihood estimation [PDF]
, 2000 We apply a general method for the estimation of completely positive maps to the 1-to-2 universal covariant cloning machine. The method is based on the maximum-likelihood principle, and makes use of random input states, along with random projective ...
A. Jamiołkowski +24 more
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Maximum Likelihood Estimation of Functionals of Discrete Distributions
, 2017 We consider the problem of estimating functionals of discrete distributions, and focus on tight nonasymptotic analysis of the worst case squared error risk of widely used estimators.
Han, Yanjun +3 more
core +1 more source
On maximum likelihood estimation of the extreme value index [PDF]
, 2004 We prove asymptotic normality of the so-called maximum likelihood estimator of the extreme value ...
de Haan, Laurens +2 more
core +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Maximum likelihood estimation in the non-ergodic fractional Vasicek model
Modern Stochastics: Theory and Applications, 2019 We investigate the fractional Vasicek model described by the stochastic differential equation $d{X_{t}}=(\alpha -\beta {X_{t}})\hspace{0.1667em}dt+\gamma \hspace{0.1667em}d{B_{t}^{H}}$, ${X_{0}}={x_{0}}$, driven by the fractional Brownian motion ${B^{H}}$
Stanislav Lohvinenko +1 more
doaj +1 more source