Results 61 to 70 of about 11,250,109 (252)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Distributed maximum power point tracking in wind micro-grids

Ingeniería, 2012
With the aim of reducing the hardware requirements in micro-grids based on wind generators, a distributed maximum power point tracking algorithm is proposed.
Carlos Andrés Ramos-Paja, Andrés Julian Saavedra-Montes, Eliana Isabel Arango Zuluaga   +2 more
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Modelling of a stand alone photovoltaic system with dedicated hybrid battery energy storage system [PDF]

, 2012
Includes abstract.Includes bibliographical references.The purpose of this thesis project was to model and simulate a stand-alone photovoltaic (PV) plant that utilized the maximum power point tracking (MPPT) technique and included a hybrid battery energy ...
Vanden Eynde, Nicholas
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Maximum power point controller for large-scale photovoltaic power plants using central inverters under partial shading conditions

, 2018
The central inverter topology based on three-level converters is widely used in large-scale photovoltaic (PV) power plants because of its simple and reliable structure and high efficiency. However, when two PV arrays are connected in series for higher dc-
Pou, Josep, Karanayil, Baburaj, Ceballos, Salvador   +2 more
core   +1 more source

Experimental validation of novel hybrid Grey Wolf Equilibrium Optimization for MPPT to improve the efficiency of solar photovoltaic system

Results in Engineering
This paper introduces a novel strategy for tracking the Maximum Power Point (MPP) using Grey Wolf Equilibrium Optimizer (GWEO) algorithm, which integrates a search mechanism of Grey Wolf Optimizer (GWO) and Equilibrium Optimizer (EO).
Feriel Abdelmalek, Hamza Afghoul, Fateh Krim, Mohit Bajaj, Vojtech Blazek   +4 more
doaj   +1 more source

Classification and Evaluation Review of Maximum Power Point Tracking Methods

Sustainable Futures, 2020
Photovoltaic (PV) systems have witnessed a rapid increment, the yield mainly relies on the working condition. In most cases, it is hard to obtain the optimal yield.
Ali Omar Baba, Guangyu Liu, Xiaohui Chen
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source