Results 131 to 140 of about 8,396,712 (346)
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
New approach to stochastic optimal control and applications to economics [PDF]
, 2005 This paper provides new insights into the solution of optimal stochastic control problems by means of a system of partial differential equations, which characterize directly the optimal control.
Rincón-Zapatero, Juan Pablo +1 more
core +1 more source
Entropy, 2017 The determination of the probability distribution function (PDF) of uncertain input and model parameters in engineering application codes is an issue of importance for uncertainty quantification methods. One of the approaches that can be used for the PDF
José-Luis Muñoz-Cobo +4 more
doaj +1 more source
Geometry of the maximum principle
, 2011 An invariant formulation of the maximum principle in optimal control is presented, and some second-order invariants are ...
Agrachev, Andrey +4 more
core +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Maximum Principle and Application of Parabolic Partial Differential Equations [PDF]
, 2012 We use the maximum principle in comparison principle and blowing up questions. In the last, we discuss the maximum principle of elliptic partial differential equation. By importing the strong maximum principle and Hopf lemma of boundary, and presents two
Fangliang, Dong
core +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
Logic of science and maximum entropy principle
, 2010 碩士當我們處理問題時，運用不同的分析方法會得到不同的結果。因此該運用何種方法做數據分析才符合科學邏輯？關於這個問題貝葉斯定理能夠給予我們一個滿意的答案；面對一問題時由已有的資訊（X）建立假說（H），再經由實驗取得數據（D）驗證假說是否成立。 然而該如何從已知的資訊建立一合理的假說就需要透過信息熵與最大熵原理的協助。薛農（Claude Elwood Shannon April 30, 1916 – February 24, 2001 ）於1948年提出了信息熵的概念來描述一事件本身的不確定度 ...
吳俊安; Wu, Chun-an
core