Results 111 to 120 of about 8,396,712 (346)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

On an Objective Basis for the Maximum Entropy Principle

open access: yesEntropy, 2015
In this letter, we elaborate on some of the issues raised by a recent paper by Neapolitan and Jiang concerning the maximum entropy (ME) principle and alternative principles for estimating probabilities consistent with known, measured constraint ...
David J. Miller, Hossein Soleimani
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Deterministic Impulse Control Maximum Principle in Operations Research: Necessary and Sufficient Optimality Conditions (replaces CentER DP 2011-052) [PDF]

open access: yes
This paper considers a class of optimal control problems that allows jumps in the state variable. We present the necessary optimality conditions of the Impulse Control Maximum Principle based on the current value formulation.
Chahim, M., Hartl, R.F., Kort, P.M.
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

The maximum principle for equations with composite coefficients

open access: yesElectronic Journal of Differential Equations, 2000
It is well-known that the maximum of the solution of a linear elliptic equation can be estimated in terms of the boundary data provided the coefficient of the gradient term is either integrable to an appropriate power or blows up like a small negative ...
Gary M. Lieberman
doaj  

Optimizing a vehicle trans-atmospheric motion using Pontryagin’s maximum principle

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2018
The task of optimizing trans-atmospheric motion of a flight vehicle in order to maximize its final velocity with prescribed finite values of the height and flight path angle is considered.
V. L. Balakin   +2 more
doaj   +1 more source

Maximum Principle for Boundary Control Problems Arising in Optimal Investment with Vintage Capital [PDF]

open access: yes
The paper concerns the study of the Pontryagin Maximum Principle for an infinite dimensional and infinite horizon boundary control problem for linear partial differential equations.
Silvia Faggian
core  

Maximum principle and optimal control

open access: yes, 2011
76 σ.Στη διπλωματική εργασία αυτή περιγράφουμε την Αρχή Μεγίστου του Pontryagin, ένα από τα πιο σημαντικά εργαλεία του Βέλτιστου Έλγχου. Βλέπουμε αναλυτικά την απόδειξη της Αρχης Μεγίστου καθώς και κάποιες γενικεύσεις της.
Παλιμέρης-Θεοδόσης, Διονύσης Π.   +1 more
core   +1 more source

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