Results 101 to 110 of about 3,605,812 (301)
Entropy, 2017 The determination of the probability distribution function (PDF) of uncertain input and model parameters in engineering application codes is an issue of importance for uncertainty quantification methods. One of the approaches that can be used for the PDF
José-Luis Muñoz-Cobo +4 more
doaj +1 more source
Optimal Cash Management Under Uncertainty [PDF]
We solve an agent's optimization problem of meeting demands for cash over time with cash deposited in bank or invested in stock. The stock pays dividends and uncertain capital gains, and a commission is incurred in buying and selling of stock.
Bensoussan, Alain +2 more
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Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl +6 more
wiley +1 more source
Spectral Methods and Maximum Principle
, 1986 Canuto, Claudio. (1986). Spectral Methods and Maximum Principle.
Canuto, Claudio
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The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta +11 more
wiley +1 more source
Filippov approach in stochastic maximum principle without differentiability assumptions
Electronic Journal of Differential Equations, 2010 In this article, we establish necessary conditions for optimality in stochastic control of systems governed by stochastic differential equations with nonsmooth coefficients.
Mokhtar Hafayed
doaj
Arthritis Care &Research, EarlyView.Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni +4 more
wiley +1 more source
Maximum Principle for Optimal Harvesting in Linear Size-Structured Population
An optimal harvesting problem for linear size-structured population dynamics is considered. A maximum principle is shown and sufficient conditions for the optimal control to be bang-bang are given.bang-bang control, maximum principle, optimal harvesting,
NOBUYUKI KATO
core +1 more source