Results 101 to 110 of about 7,132,105 (326)
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Optimizing a vehicle trans-atmospheric motion using Pontryagin’s maximum principle
The task of optimizing trans-atmospheric motion of a flight vehicle in order to maximize its final velocity with prescribed finite values of the height and flight path angle is considered.
V. L. Balakin +2 more
doaj +1 more source
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
The strong maximum principle for Schrödinger operators on fractals
We prove a strong maximum principle for Schrödinger operators defined on a class of postcritically finite fractal sets and their blowups without boundary.
Ionescu Marius V. +2 more
doaj +1 more source
Maximum principle for near-optimality of stochastic delay control problem
This paper is concerned with near-optimality for stochastic control problems of linear delay systems with convex control domain and controlled diffusion. Necessary and sufficient conditions for a control to be near-optimal are established by Pontryagin’s
Feng Zhang
doaj +1 more source
Dynamic Programming, Maximum Principle and Vintage Capital [PDF]
We present an application of the Dynamic Programming (DP) and of the Maximum Principle (MP) to solve an optimization over time when the production function is linear in the stock of capital (Ak model). Two views of capital are considered.
Fabbri, Giorgio, Iacopetta, Maurizio
core +1 more source
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti +19 more
wiley +1 more source
MAXIMUM PRINCIPLE FOR SUBSONIC FLOW WITH VARIABLE ENTROPY
Maximum principle for subsonic flow is fair for stationary irrotational subsonic gas flows. According to this principle, if the value of the velocity is not constant everywhere, then its maximum is achieved on the boundary and only on the boundary of the
G. B. Sizykh
doaj
Costly Sanctions and the Maximum Penalty Principle [PDF]
We study the problem of deterring undesirable behavior in a moral hazard framework with risk averse individuals, noisy information and costly sanctions.
Claude Fluet, Dominique Demougin
core
Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni +7 more
wiley +1 more source

