Results 81 to 90 of about 7,132,105 (326)
Markov processes follow from the principle of Maximum Caliber
, 2011 Markov models are widely used to describe processes of stochastic dynamics. Here, we show that Markov models are a natural consequence of the dynamical principle of Maximum Caliber.
Brockwell P. J. +6 more
core +1 more source
Journal of the Australian Mathematical Society, 1979 AbstractLet K be a nonempty compact set in a Hausdorff locally convex space, and F a nonempty family of upper semicontinuous convex-like functions from K into [–∞, ∞). K is partially ordered by F in a natural manner. It is shown among other things that each isotone, upper semicontinuous and convex-like function g: K → [ – ∞, ∞) attains its K-maximum at
openaire +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
A Reappraisal of the Principle of Maximum Power
EcologiesLiving organisms continuously capture and transform free energy to survive and grow. The Maximum Power Principle (MPP) states that life evolves to maximize power—the rate of energy acquisition and conversion into useful forms—within prevailing ...
Alberto Gianinetti
doaj +1 more source
Optimal Control of Polymer Flooding Based on Maximum Principle
Journal of Applied Mathematics, 2012 Polymer flooding is one of the most important technologies for enhanced oil recovery (EOR). In this paper, an optimal control model of distributed parameter systems (DPSs) for polymer injection strategies is established, which involves the performance ...
Yang Lei +4 more
doaj +1 more source
A Clustering Method Based on the Maximum Entropy Principle
Entropy, 2015 Clustering is an unsupervised process to determine which unlabeled objects in a set share interesting properties. The objects are grouped into k subsets (clusters) whose elements optimize a proximity measure.
Edwin Aldana-Bobadilla +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Maximum principle and the fourth order boundary value problem
Mathematical Modelling and Analysis, 2011 This paper is devoted to the study the nonlinear boundary value problem . We state a maximum principle related with the operator and apply it to prove the existence and approximation of solutions to the problem (i), (ii), in presence of properly ordered
Inara Yermachenko
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source