Results 61 to 70 of about 5,329,290 (309)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Maximum Configuration Principle for Driven Systems with Arbitrary Driving

open access: yesEntropy, 2018
Depending on context, the term entropy is used for a thermodynamic quantity, a measure of available choice, a quantity to measure information, or, in the context of statistical inference, a maximum configuration predictor.
Rudolf Hanel, Stefan Thurner
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Maximum Error Parallel Detection Method Based on Locality Principle [PDF]

open access: yesJisuanji kexue
Floating-point numbers use a finite number of digits to represent infinite real numbers for computation,so floating-point computation is inherently inaccurate,which can be measured by the maximum error.The traditional floating-point maximum error ...
JI Liguang, YANG Hongru, ZHOU Yuchang, CUI Mengqi, HE Haotian, XU Jinchen
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A maximum principle for second order parabolic system

open access: yesJournal of Numerical Analysis and Approximation Theory, 1976
Not available.
Anton Mureşan
doaj   +2 more sources

A Reappraisal of the Principle of Maximum Power

open access: yesEcologies
Living organisms continuously capture and transform free energy to survive and grow. The Maximum Power Principle (MPP) states that life evolves to maximize power—the rate of energy acquisition and conversion into useful forms—within prevailing ...
Alberto Gianinetti
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Stochastic maximum principle for SPDEs with delay [PDF]

open access: yes, 2016
In this paper we develop necessary conditions for optimality, in the form of the Pontryagin maximum principle, for the optimal control problem of a class of infinite dimensional evolution equations with delay in the state. In the cost functional we allow
G. Guatteri, F. Masiero, Carlo Orrieri
semanticscholar   +1 more source

Mean-Field Pontryagin Maximum Principle [PDF]

open access: yesJournal of Optimization Theory and Applications, 2015
We derive a maximum principle for optimal control problems with constraints given by the coupling of a system of ordinary differential equations and a partial differential equation of Vlasov type with smooth interaction kernel.
M. Bongini   +3 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy